Cincinnati Children's Research Foundation Postdoctoral Fellow in vascular development- hemangiomas The Visual Systems Group at CCHMC has an opening for a Postdoctoral Fellow. The Lang laboratory is focused on elucidating mechanisms of vascular development and for this project is interested in understanding how macrophages influence formation of the lymphatic vessels and whether they might play a role in formation of hemangiomas. This project will be executed in collaboration with Dr. Belinda Dicke, a surgeon within the Hemangioma and Vascular Malformations, and Colorectal Centers at Cincinnati Children’s Hospital. Our previous publications in this area include: 1. Stefater JAI, Lewkowich I, Rao S, Mariggi G, Carpenter AC, et al. (2011) Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells. Nature 474: 511-515. 2. Gordon EJ, Rao S, Pollard JW, Nutt SL, Lang RA, et al. (2010) Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development 137: 3899-3910. 3. Phng LK, Potente M, Leslie JD, Babbage J, Nyqvist D, et al. (2009) Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis. Dev Cell 16: 70-82. 4. Rao S, Lobov IB, Vallance JE, Tsujikawa K, Shiojima I, et al. (2007) Obligatory participation of macrophages in an angiopoietin 2-mediated cell death switch. Development 134: 4449-4458. 5. Lobov IB, Rao S, Carroll TJ, Vallance JE, Ito M, et al. (2005) WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature. Nature 437: 417-421. Details about project areas can be found at: http://www.cincinnatichildrens.org/bio/l/richard-lang/ http://www.cincinnatichildrens.org/research/divisions/o/ophthalmology/labs/lang/default/ The Visual Systems Group is a high-energy, dynamic, and interactive environment that is interested in recruiting self-motivated individuals with the drive to succeed and the desire to be competitive at the international level. Candidates with a strong background in immunology, molecular biology, informatics, genomics, cellular biology and/or signal transduction are encouraged to apply. Please apply online for job number 56106 at http://www.cincinnatichildrens.org/careers/apply/default.htm Cincinnati Childrens Hospital Medical Center is an Affirmative Action/Equal Opportunity Institution. Women and minorities are encouraged to apply. Contact: Cindy Bachurski, PhD Cincinnati Children's Research Foundation 3333 Burnet Ave. Cincinnati, OH 45229 United States Email: Send your resume/CV
